aching
achy
agonised
agonising
agonized
agonizing
bad
biting
bitter
chafed
excruciating
galled
harrowing
itchy
poignant
racking
raw
saddle-sore
sensitive
sore
tender
torturesome
torturing
torturous
traumatic
uncomfortable
unpleasant
wrenching
Herculean
acute
affecting
afflictive
aggravating
algetic
annoying
arduous
assiduous
atrocious
backbreaking
besetting
bleak
bothersome
burdensome
burning
careful
cheerless
comfortless
conscientious
cramping
cruel
crushing
demanding
deplorable
depressing
depressive
detailed
difficult
diligent
discomforting
dismal
dismaying
disquieting
distasteful
distressful
distressing
disturbing
doleful
dangerous
intense
terrible
disdainful
gainful
painfree
painless